1st Polish Yeast Conference, Rzeszow, June 22-24, 2022


1st Polish Yeast Conference, Rzeszow

June 22-24, 2022 (Wednesday - Friday)

 

 

Day 1 (June 22) 

 

9.00 – 16.00

 

Registration

13.00 – 13.15

 

Opening Ceremony

Andriy Sibirny – Chair of the Conference

Idalia Kasprzyk – Vice-Rector of the University of Rzeszow

Roza Kucharczyk – Deputy Director of General Affairs of Institute of Biochemistry and Biophysics, Polish Academy of Sciences

Hiroshi Takagi – Vice-Chair of International Commission on Yeasts

Terrance G. Cooper – Secretary of the Financial and Policy Committee of the International Yeast Research Community

Grzegorz Wegrzyn – Scientific Excellence Council

 

13.15 – 14.00

 

Keynote Lecture 1

Terrance G. Cooper, University of Tennessee Health Science Center, Memphis, Tennessee, USA

Multivariant global control of the major nitrogen-responsive transcription activator, Gln3

 

14.00 – 15.30

 

Session 1 Yeast cell biology and transport

Chairs: Renata Zadrag-Tecza, University of Rzeszow, Rzeszow
              
 Ewa Maciaszczyk-Dziubinska, University of Wroclaw , Wroclaw

14.00 – 14.15

 

Michal Malecki, University of Warsaw, Warsaw

Role of uridylation in cytoplasmic mRNA Decay

14.15 – 14.30

 

Marek Skoneczny, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

New import pathway to peroxisomes: some answers, more questions

14.30 – 14.45

 

Renata Zadrag-Tecza, University of Rzeszow, Rzeszow

Cell size implications for the reproductive capacity of yeast cells

14.45 – 15.00

 

Zbigniew Lazar, Wroclaw University of Environmental and Life Sciences, Wroclaw

Characterization of sugar and glycerol metabolism in the yeast Yarrowia lipolytica

15.00 – 15.15

 

Aneta Urbanek, University of Wroclaw, Wroclaw

Interplay between Candida albicans transporters, plasma membrane and cell wall

15.15 – 15.30

 

Marta Semkiv, Institute of Cell Biology, NAS of Ukraine, Lviv

Autophagic degradation of cytosolic proteins in the methylotrophic yeast Komagataealla phaffii

 

15.30 – 16.00

 

Coffee break

 

16.00 – 17.30

 

Session 2 Sensing, signalling and stress response

 

 

Chairs: Maciej Wnuk, University of Rzeszow, Rzeszow
Marek Skoneczny,
Institute of Biochemistry and Biophysics,
Polish Academy of Sciences, Warsaw

16.00 – 16.30

 

Oleh Stasyk, Institute of Cell Biology, NAS of Ukraine, Lviv

Glucose sensing and signaling in the methylotrophic yeast Ogataea polymorpha

16.30 – 16.45

 

Jennifer Tate, Tennessee Health Science Center, Memphis, Tennessee, USA

N-terminal Gln3 phosphorylation/dephosphorylation in the control of Gln3 localization

16.45 – 17.00

 

Kamilla Grzywacz, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan

Emerging functions of ribosome-associated noncoding RNAs during stress response in Saccharomyces cerevisiae

17.00 – 17.15

 

Krzysztof Liberek, University of Gdansk, Gdansk

Yeast chaperones in refolding of proteins from aggregates

17.15 – 17.30

 

Malgorzata Adamczyk, Warsaw University of Technology, Warsaw

New role of RNA polymerase III in shaping metabolic network activity and stress response in Saccharomyces cerevisiae

 

17.30 – 19.00

 

Session 3 Genetic Control of Cellular Processes

 

 

Chairs: Marek Tchorzewski,  Maria Curie-Skłodowska University in Lublin, Lublin
Kamilla Grzywacz,
Institute of Bioorganic Chemistry,
Polish Academy of Sciences, Poznan

17.30 – 17.50

 

Marek Tchorzewski, Maria Curie-Sklodowska University in Lublin, Lublin

The influence of ricin-mediated rRNA depurination on the translational machinery using Saccharomyces cerevisiae as experimental model

17.50 – 18.05

 

Małgorzata Ciesla, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

RNA polymerase III transcription, novel layers of regulation

18.05 – 18.20

 

Ulrike Topf, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

Crosstalk between mitochondria and cytosolic translation machinery

18.20 – 18.35

 

Pawel Golik, Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Warsaw

Mitochondrial RNA degradation and stability in Candida albicans and the evolution of yeast nucleo-mitochondrial interactions

18.35 – 18.50

 

Dorota Rzechonek, Wroclaw University of Environmental and Life Sciences, Wroclaw

Regulation of erythritol utilisation in Yarrowia lipolytica

19.00

 

Subcarpathian Accordion Quintet "Ambitus V" Concert
in the University of Rzeszów Senate Room

 

Day 2 (June 23)

 

9.00 – 10.30

 

Session 4 Genome maintenance

 

 

Chairs: Adrianna Skoneczna, Institute of Biochemistry and Biophysics,
Polish Academy of Sciences, Warsaw

Robert Wysocki,
University of Wroclaw, Wroclaw

9:00 – 9:20

 

Adrianna Skoneczna, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

Post-translational regulation of Rad51 recombinase in yeast S. cerevisiae

9:20 – 9:40

 

Dorota Dziadkowiec, Faculty of Biotechnology, University of Wroclaw, Wroclaw  

The role of yeast SWI2/SNF2 DNA dependent translocases in genome stability maintenance

9:40 – 10:00

 

Michal Dmowski, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

Contribution of non-catalytic subunits of the helicase-polymerase complex to the maintenance of genome stability in yeast

10:0010:15

 

Ireneusz Litwin, Scientific Excellence Hub - Centre for DNA Repair and Replication, University of Wroclaw, Wroclaw

Identification of new cohesin interactors in yeast

10:15 – 10:30

 

Karol Kramarz, Scientific Excellence Hub - Centre for DNA Repair and Replication, University of Wroclaw, Wroclaw

Impact of SUMOylation at replication stress sites in fission yeast

 

10.30 – 11.00

 

Coffee break

 

11.00 – 12.30

 

Session 5 Yeast as a model of human diseases and drug testing

 

 

Chairs: Teresa Zoladek, Institute of Biochemistry and Biophysics,
Polish Academy of Sciences, Warsaw

Roza Kucharczyk,
Institute of Biochemistry and Biophysics,
Polish Academy of Sciences, Warsaw

11.00 – 11.30

 

Sylvie Friant, University of Strasbourg, Strasbourg, France

Humanization of yeast cells to study human proteins and patient mutations in rare diseases

11.30 – 11.45

 

Roza Kucharczyk, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

Mechanisms of ATP synthase defects due to mutations in mitochondrial ATP6 gene - yeast studies

11.45 – 12.00

 

Joanna Kaminska, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

Helpful yeasts - how to find therapy for patients with Vps13 proteins deficit?

12.00 – 12.15

 

Andrzej Kochanski, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw

Pathogenic effect of GDAP1 mutations causative for CMT4A disease in a yeast model

12.15 – 12.30

 

Monika Staniszewska, Warsaw University of Technology, Warsaw

New trends in search for antifungal therapies

 

12.30 – 13.30

 

Lunch

 

13.30 – 15.00

 

Session 6 Yeast biodiversity and evolution

 

 

Chairs: Ryszard Korona, Jagielonian University, Cracow
Jaroslaw Marszalek,
University of Gdansk, Gdansk

13.30 – 13.45

 

Lubomir Tomaska, Comenius University in Bratislava, Slovakia

A runaway evolution of telomeres in ascomycetous yeasts

13.45 – 14.00

 

Jaroslaw Marszalek, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk

Evolutionary Biochemistry of yeast Hsp70/J-protein chaperones substrate binding cycle

14.00 – 14.15

 

Szymon Kaczanowski, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

Yeast as a model of evolution of apoptosis

14.15 – 14.30

 

Chiranjit Panja, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

YOR020W-A (MCO10): characterizing the unknown “subunit L” of mitochondrial ATP synthase
of
Saccharomyces cerevisiae

14.30 – 14.45

 

Monika Opalek, Institute of Environmental Sciences, Jagiellonian University, Cracow

Fitness advantage of phenotypic heterogeneity in Saccharomyces cerevisiae populations

14.45 – 15.00

 

Marcin Plech, University of Edinburgh, Edinburgh, United Kingdon

Deep mutational scanning of human mendelian disease genes in yeast

15.30 – 18.00

 

Poster Session with coffee and cakes

18.00 – 23.00

 

Banquet

 

Day 3 (June 24)

 

8.30 – 9.15

 

Keynote Lecture 2

Volkmar Passoth, Swedish University of Agricultural Sciences, Uppsala, Sweden

Oleaginous yeasts for biochemicals, feed and food from lignocellulose

 

9.15 – 10.45

 

Session 7 Yeast Biotechnology

 

 

Chairs: Ewelina Celinska, Poznan University of Life Sciences, Poznan
Zbigniew Lazar,
Wroclaw University of Environmental and Life Sciences, Wroclaw

9.15 – 9.45

 

Hiroshi Takagi, Nara Institute of Science and Technology, Japan

Proline new science and technology in yeast

9.45 – 10.00

 

Olena Dmytruk, University of Rzeszow, Rzeszow

Production of the bacterial antibiotics roseoflavin and aminoriboflavin by recombinant strains of the yeasts Candida famata and Komagataella phaffii

10.00 – 10.15

 

Katarzyna Kosiorowska, Wroclaw University of Environmental and Life Sciences, Wroclaw

Metabolic engineering of Yarrowia lipolytica yeast for poly(ethylene terephthalate) degradation

10.15 – 10.30

 

Aksyniia Tsaruk, Institute of Cell Biology, NAS of Ukraine, Lviv

The effect of carbon source, aeration and pH control on L-lactic acid production by methylotrophic yeast Ogataea polymorpha

10.30 – 10.45

 

Andriy Sibirny, University of Rzeszow, Rzeszow

Construction of the humanized strains of Komagataella phaffii producing intracellular, secreted and surface displayed SARS-CoV-2 antigens as potential vaccines against COVID-19

 

10.45 – 11.15

 

Coffee break

 

11.15 – 12.45

 

Session 7 Yeast Biotechnology (continued)

 

 

Chairs: Aleksandra Mironczuk, Wroclaw University of Environmental and Life Sciences, Wroclaw
Justyna Ruchala, University of Rzeszow, Rzeszow

11.15 – 11.30

 

Ewelina Celinska, Poznan University of Life Sciences, Poznan

Omics-guided engineering of a secretory pathway for enhanced synthesis of secretory proteins
in
Yarrowia lipolytica

11.30 – 11.45

 

Patrick Fickers, Liege University, Liege, Belgium

Erythritol metabolism: from fundamental research to biotech application

11.45 – 12.00

 

Milan Certik, Slovak University of Technology, Brtislava, Slovakia

Yarrowia lipolytica as a platform for production of tailor-made lipids

12.00 – 12.15

 

Mateusz Szczepanczyk, Wroclaw University of Environmental and Life Sciences, Wroclaw

Molecular mechanism of polyols assimilation by yeast Yarrowia lipolytica

12.15 – 12.25

 

Justyna Ruchala, University of Rzeszow, Rzeszow

Thermotolerant yeast Ogataea polymorpha as promising producer of the second generation ethanol

12.25 – 12.35

 

Maria Gorczyca, Poznan University of Life Sciences, Poznan

Co-expression of selected transcription factors modulates synthesis of heterologous proteins in Yarrowia lipolytica under stress conditions

12.35 – 12.45

 

Marcin Sypka, Lodz University of Technology, Lodz

Cold-adapted yeasts - the source of valuable biomolecules

 

12.45 – 13.45

 

Lunch

 

13.45 – 15.15

 

Session 8 Pathogenic and probiotic yeasts

 

 

Chairs: Monika Staniszewska, Warsaw University of Technology, Warsaw
Maria Rapala-Kozik,
Jagielonian University, Cracow

13.45 – 14.00

 

Maria Rapala-Kozik, Jagiellonian University, Cracow

Living together - the role of Candida albicans in the formation of polymicrobial biofilm

14.00 – 14.15

 

Justyna Karkowska-Kuleta, Jagiellonian University, Cracow

The host put up against the pathogen’s wall - the function of surface-exposed Candida molecules

14.15 – 14.25

 

Marcin Zawrotniak, Jagiellonian University, Cracow

Neutrophil responses to fungal infections

14.25 – 14.35

 

Maciej Maslyk, The John Paul II Catholic University of Lublin, Lublin

In search of effective anti-Candida albicans agents

14.35 – 14.45

 

Monika Kordowska-Wiater, University of Life Sciences, Lublin

Application of Saccharomyces cerevisiae var. boulardii in probiotic food - study on legume sprouts

14.45 – 15.00

 

Malgorzata Cytrynska, Maria Curie-Sklodowska University in Lublin, Lublin

Close encounters of Candida albicans with different antimicrobial peptides and proteins

15.00 – 15.15

 

Dorota Kregiel, Lodz University of Technology, Lodz

Production and biological activity of pulcherrimin from Metschnikowia pulcherrima clade

 

15.15 – 15.45

 

Oral presentations of the best poster presenting authors
(young scientists PhD/postdocs < 35yo.)

 

15.45 – 16.00

 

Best Poster Awards. Closing Ceremony